Lymphosarcoma with a positive Paul-Bunnell test.

Specificity of the Paul-Bunnell test.

A previously healthy 1 8-year-old student developed a slight sore throat and malaise, followed two weeks later by some shortness of breath and a feeling of tightness in her face. These latter symptoms were more marked when she was lying flat. Examination at time of admission to hospital revealed marked bilateral jugular venous distension with facial swelling and cyanosis. A few small (1 cm.) ly...

A quick method of performing the Paul-Bunnell test.

(4) In the remaining tubes of each row is placed 0.5 ml. of 0.85% sodium chloride. (5) To the first tube of each row 0.1 ml. of serum is added and mixed thoroughly. (6) Then 0.5 ml. of the diluted serum is carried over into tube 2 and so on until tube 10, the last 0.5 ml. being discarded. (7) To each tube 0.5 ml. of washed fresh sheep cells is added, thus giving a final serum dilution of 1:20 u...

A comparison of the Monospot with the Paul-Bunnell test in infectious mononucleosis and other diseases.

The Monospot is a spot test designed for the diagnosis of infectious mononucleosis and its efficacy has been compared with that of the standard Paul-Bunnell test. Three out of 210 (1.4%) sera from normal persons and persons suffering from diseases other than infectious mononucleosis gave ;false' positive results when compared with the Paul-Bunnell test. Using 38 sera from patients with strong c...

Paul-Bunnell Test in the Diagnosis of Glandular Fever with Report on Seven Cases

Paul-Bunnell antigen and a possible mechanism of formation of heterophile antibodies in patients with infectious mononucleosis.

Sera of patients with infectious mononucleosis contain heterophile anti-Paul- Bunnell (PB) antibodies to erythrocytes of numerous mammalian species. Evidence is presented that the corresponding antigen of bovine erythrocytes is not, as previously described, a single molecule, but a series of glycoproteins with glycans terminated with N-glycolylneuraminic acid (Neu5Gc). The latter compound shoul...